A temporo-spatial pharmacometabolomics method to characterize pharmacokinetics and pharmacodynamics in the brain microregions by using ambient mass spectrometry imaging

The brain is the most advanced organ with various complex structural and functional microregions. It is often challenging to understand what and where the molecular events would occur for a given drug treatment in the brain. Herein, a temporo-spatial pharmacometabolomics method was proposed based on...

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Detalles Bibliográficos
Autores principales: Liu, Dan, Huang, Jianpeng, Gao, Shanshan, Jin, Hongtao, He, Jiuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366215/
https://www.ncbi.nlm.nih.gov/pubmed/35967273
http://dx.doi.org/10.1016/j.apsb.2022.03.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366215/
https://www.ncbi.nlm.nih.gov/pubmed/35967273
http://dx.doi.org/10.1016/j.apsb.2022.03.018

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