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A polyphenol-assisted IL-10 mRNA delivery system for ulcerative colitis

With the development of synthesis technology, modified messenger RNA (mRNA) has emerged as a novel category of therapeutic agents for a broad of diseases. However, effective intracellular delivery of mRNA remains challenging, especially for its sensitivity to enzymatic degradation. Here, we propose...

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Detalles Bibliográficos
Autores principales: Chen, Zhejie, Hao, Wei, Gao, Caifang, Zhou, Yangyang, Zhang, Chen, Zhang, Jinming, Wang, Ruibing, Wang, Yitao, Wang, Shengpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366313/
https://www.ncbi.nlm.nih.gov/pubmed/35967288
http://dx.doi.org/10.1016/j.apsb.2022.03.025