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Broadening the spectrum of ivermectin: Its effect on Trypanosoma cruzi and related trypanosomatids

Chagas disease is an endemic American parasitosis, caused by Trypanosoma cruzi. The current therapies, benznidazole (BZN) and nifurtimox (NFX), show limited efficacy and multiple side effects. Thus, there is a need to develop new trypanocidal strategies. Ivermectin (IVM) is a broad-spectrum antipara...

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Detalles Bibliográficos
Autores principales: Fraccaroli, Laura, Ruiz, María Daniela, Perdomo, Virginia Gabriela, Clausi, Agustina Nicole, Balcazar, Darío Emmanuel, Larocca, Luciana, Carrillo, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366347/
https://www.ncbi.nlm.nih.gov/pubmed/35967842
http://dx.doi.org/10.3389/fcimb.2022.885268