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Polyethylene glycol 20 kDa-induced vacuolation does not impair phagocytic function of human monocyte-derived macrophages

Conjugation to polyethylene glycol (PEG) is commonly used to enhance drug delivery and efficacy by extending the half-life of the drug molecule. This has important implications for reducing treatment burden in diseases that require chronic prophylaxis, such as hemophilia. Clearance of PEG molecules...

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Detalles Bibliográficos
Autores principales: Schoenbrunn, Anne, Juelke, Kerstin, Reipert, Birgit M., Horling, Frank, Turecek, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366735/
https://www.ncbi.nlm.nih.gov/pubmed/35967311
http://dx.doi.org/10.3389/fimmu.2022.894411