CHIKV infection reprograms codon optimality to favor viral RNA translation by altering the tRNA epitranscriptome

Ample evidence indicates that codon usage bias regulates gene expression. How viruses, such as the emerging mosquito-borne Chikungunya virus (CHIKV), express their genomes at high levels despite an enrichment in rare codons remains a puzzling question. Using ribosome footprinting, we analyze transla...

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Detalles Bibliográficos
Autores principales: Jungfleisch, Jennifer, Böttcher, René, Talló-Parra, Marc, Pérez-Vilaró, Gemma, Merits, Andres, Novoa, Eva Maria, Díez, Juana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366759/
https://www.ncbi.nlm.nih.gov/pubmed/35953468
http://dx.doi.org/10.1038/s41467-022-31835-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366759/
https://www.ncbi.nlm.nih.gov/pubmed/35953468
http://dx.doi.org/10.1038/s41467-022-31835-x

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