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CHIKV infection reprograms codon optimality to favor viral RNA translation by altering the tRNA epitranscriptome
Ample evidence indicates that codon usage bias regulates gene expression. How viruses, such as the emerging mosquito-borne Chikungunya virus (CHIKV), express their genomes at high levels despite an enrichment in rare codons remains a puzzling question. Using ribosome footprinting, we analyze transla...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366759/ https://www.ncbi.nlm.nih.gov/pubmed/35953468 http://dx.doi.org/10.1038/s41467-022-31835-x |