A disturbed balance between blood complement protective factors (FH, ApoE) and common pathway effectors (C5a, TCC) in acute COVID-19 and during convalesce

A complement effect on homeostasis during infection is determined by both cytotoxic (activate complement component 5 (C5a) terminal cytotoxic complex (TCC)), and cytoprotective elements (complement factor H (FH), as well as apolipoprotein E (ApoE)). Here, we investigated the gap in knowledge in thei...

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Detalles Bibliográficos
Autores principales: Laudanski, Krzysztof, Okeke, Tony, Siddiq, Kumal, Hajj, Jihane, Restrepo, Mariana, Gullipalli, Damodar, Song, Wen-chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366819/
https://www.ncbi.nlm.nih.gov/pubmed/35953544
http://dx.doi.org/10.1038/s41598-022-17011-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366819/
https://www.ncbi.nlm.nih.gov/pubmed/35953544
http://dx.doi.org/10.1038/s41598-022-17011-7

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