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A disturbed balance between blood complement protective factors (FH, ApoE) and common pathway effectors (C5a, TCC) in acute COVID-19 and during convalesce
A complement effect on homeostasis during infection is determined by both cytotoxic (activate complement component 5 (C5a) terminal cytotoxic complex (TCC)), and cytoprotective elements (complement factor H (FH), as well as apolipoprotein E (ApoE)). Here, we investigated the gap in knowledge in thei...
Autores principales: | Laudanski, Krzysztof, Okeke, Tony, Siddiq, Kumal, Hajj, Jihane, Restrepo, Mariana, Gullipalli, Damodar, Song, Wen-chao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366819/ https://www.ncbi.nlm.nih.gov/pubmed/35953544 http://dx.doi.org/10.1038/s41598-022-17011-7 |
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