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ELISA based assays to measure adenosine deaminases concentration in serum and saliva for the diagnosis of ADA2 deficiency and cancer

Adenosine deaminases (ADAs) are enzymes of purine metabolism converting adenosine to inosine. There are two types of ADAs in humans ADA1 and ADA2. While both ADA1 and ADA2 share the same substrate, they differ in expression, cellular localization, and catalytic properties. The genetic deficiency of...

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Detalles Bibliográficos
Autores principales: Luo, Wenwen, Dong, Liang, Chen, Fenghong, Lei, Wenbin, He, Liya, Zhou, Qing, Lamy, Thierry, Zavialov, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366848/
https://www.ncbi.nlm.nih.gov/pubmed/35967411
http://dx.doi.org/10.3389/fimmu.2022.928438