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Altered expression of Tim family molecules and an imbalanced ratio of Tim-3 to Tim-1 expression in patients with type 1 diabetes

BACKGROUND: T-cell immunoglobulin and mucin domain (Tim) proteins are immunomodulatory molecules that play key roles in the regulation of T-cell activation. Published studies have reported that Tim molecules are involved in the pathogenesis of certain autoimmune diseases. Type 1 diabetes (T1D) is an...

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Detalles Bibliográficos
Autores principales: Liu, Yikai, Chen, Zhiying, Xiao, Yang, Chen, Hongzhi, Zhou, Zhiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366857/
https://www.ncbi.nlm.nih.gov/pubmed/35966054
http://dx.doi.org/10.3389/fendo.2022.937109