Contribution of model organism phenotypes to the computational identification of human disease genes

Computing phenotypic similarity helps identify new disease genes and diagnose rare diseases. Genotype–phenotype data from orthologous genes in model organisms can compensate for lack of human data and increase genome coverage. In the past decade, cross-species phenotype comparisons have proven valub...

Descripción completa

Detalles Bibliográficos
Autores principales: Alghamdi, Sarah M., Schofield, Paul N., Hoehndorf, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366895/
https://www.ncbi.nlm.nih.gov/pubmed/35758016
http://dx.doi.org/10.1242/dmm.049441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366895/
https://www.ncbi.nlm.nih.gov/pubmed/35758016
http://dx.doi.org/10.1242/dmm.049441

Ejemplares similares