Hydrochloride Salt of the GABAkine KRM-II-81

[Image: see text] Imidazodiazepine (5-(8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazole[1,5-α][1,4]diazepin-3-yl) oxazole or KRM-II-81) is a potentiator of GABA(A) receptors (a GABAkine) undergoing preparation for clinical development. KRM-II-81 is active against many seizure and pain models in roden...

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Detalles Bibliográficos
Autores principales: Mian, Md Yeunus, Divović, Branka, Sharmin, Dishary, Pandey, Kamal P., Golani, Lalit K., Tiruveedhula, V. V. N. Phani Babu, Cerne, Rok, Smith, Jodi L., Ping, Xingjie, Jin, Xiaoming, Imler, Gregory H., Deschamps, Jeffrey R., Lippa, Arnold, Cook, James M., Savić, Miroslav M., Rowlett, James, Witkin, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366947/
https://www.ncbi.nlm.nih.gov/pubmed/35967038
http://dx.doi.org/10.1021/acsomega.2c03029

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