Cargando…

The telomere maintenance mechanism spectrum and its dynamics in gliomas

BACKGROUND: The activation of the telomere maintenance mechanism (TMM) is one of the critical drivers of cancer cell immortality. In gliomas, TERT expression and TERT promoter mutation are considered to reliably indicate telomerase activation, while ATRX mutation and/or loss indicates an alternative...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Sojin, Chowdhury, Tamrin, Yu, Hyeon Jong, Kahng, Jee Ye, Lee, Chae Eun, Choi, Seung Ah., Kim, Kyung-Min, Kang, Ho, Lee, Joo Ho, Lee, Soon-Tae, Won, Jae-Kyung, Kim, Kyung Hyun, Kim, Min-Sung, Lee, Ji Yeoun, Kim, Jin Wook, Kim, Yong-Hwy, Kim, Tae Min, Choi, Seung Hong, Phi, Ji Hoon, Shin, Young-Kyoung, Ku, Ja-Lok, Lee, Sungyoung, Yun, Hongseok, Lee, Hwajin, Kim, Dokyoung, Kim, Kyoungmi, Hur, Junho K., Park, Sung-Hye, Kim, Seung-Ki, Park, Chul-Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367055/
https://www.ncbi.nlm.nih.gov/pubmed/35953846
http://dx.doi.org/10.1186/s13073-022-01095-x