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Detection of Microsatellite Instability in Colonoscopic Biopsies and Postal Urine Samples from Lynch Syndrome Cancer Patients Using a Multiplex PCR Assay

SIMPLE SUMMARY: Lynch syndrome is caused by inherited defects in genes which repair DNA, and predisposes affected individuals to cancers of the bowel, endometrium (uterus lining), and urinary tract, among others. Most of these cancers exhibit a characteristic pattern of DNA instability in Lynch synd...

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Detalles Bibliográficos
Autores principales: Phelps, Rachel, Gallon, Richard, Hayes, Christine, Glover, Eli, Gibson, Philip, Edidi, Ibrahim, Lee, Tom, Mills, Sarah, Shaw, Adam, Heer, Rakesh, Ralte, Angela, McAnulty, Ciaron, Santibanez-Koref, Mauro, Burn, John, Jackson, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367254/
https://www.ncbi.nlm.nih.gov/pubmed/35954501
http://dx.doi.org/10.3390/cancers14153838