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PARP1 Might Substitute HSF1 to Reactivate Latent HIV-1 by Binding to Heat Shock Element

At present, the barrier to HIV-1 functional cure is the persistence of HIV-1 reservoirs. The “shock (reversing latency) and kill (antiretroviral therapy)” strategy sheds light on reducing or eliminating the latent reservoir of HIV-1. However, the current limits of latency-reversing agents (LRAs) are...

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Detalles Bibliográficos
Autores principales: Xu, Xinfeng, Lin, Yingtong, Zeng, Xiaoyun, Yang, Chan, Duan, Siqin, Ding, Liqiong, Lu, Wanzhen, Lin, Jian, Pan, Xiaoyan, Ma, Xiancai, Liu, Shuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367301/
https://www.ncbi.nlm.nih.gov/pubmed/35954175
http://dx.doi.org/10.3390/cells11152331