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Pten and p53 Loss in the Mouse Lung Causes Adenocarcinoma and Sarcomatoid Carcinoma

SIMPLE SUMMARY: Lung cancer is the world leading cause of cancer death. Therefore, a better understanding of the disease is needed to improve patient survival. In this work, we have deleted the tumor suppressor genes Pten and Trp53 in adult mouse lungs to analyze its impact on tumor formation. Doubl...

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Detalles Bibliográficos
Autores principales: Lázaro, Sara, Lorz, Corina, Enguita, Ana Belén, Seller, Iván, Paramio, Jesús M., Santos, Mirentxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367331/
https://www.ncbi.nlm.nih.gov/pubmed/35954335
http://dx.doi.org/10.3390/cancers14153671