CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence

SIMPLE SUMMARY: The hyaluronan receptor CD44 has an important role in glioblastoma multiforme (GBM) progression, but the precise mechanisms have not been elucidated. We have analyzed U251MG glioma cells, expressing CD44 or not, and grown in stem cell-like enriched spheres. Our results revealed that...

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Detalles Bibliográficos
Autores principales: Kolliopoulos, Constantinos, Ali, Mohamad Moustafa, Castillejo-Lopez, Casimiro, Heldin, Carl-Henrik, Heldin, Paraskevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367353/
https://www.ncbi.nlm.nih.gov/pubmed/35954411
http://dx.doi.org/10.3390/cancers14153747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367353/
https://www.ncbi.nlm.nih.gov/pubmed/35954411
http://dx.doi.org/10.3390/cancers14153747

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