Pseudoislet Aggregation of Pancreatic β-Cells Improves Glucose Stimulated Insulin Secretion by Altering Glucose Metabolism and Increasing ATP Production

Appropriate glucose-stimulated insulin secretion (GSIS) by pancreatic β-cells is an essential component of blood glucose homeostasis. Configuration of β-cells as 3D pseudoislets (PI) improves the GSIS response compared to 2D monolayer (ML) culture. The aim of this study was to determine the underlyi...

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Detalles Bibliográficos
Autores principales: Cornell, Deborah, Miwa, Satomi, Georgiou, Merilin, Anderson, Scott James, Honkanen-Scott, Minna, Shaw, James A. M., Arden, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367366/
https://www.ncbi.nlm.nih.gov/pubmed/35954174
http://dx.doi.org/10.3390/cells11152330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367366/
https://www.ncbi.nlm.nih.gov/pubmed/35954174
http://dx.doi.org/10.3390/cells11152330

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