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Histone Deacetylase Inhibitors Restore Cancer Cell Sensitivity towards T Lymphocytes Mediated Cytotoxicity in Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive pancreatic cancer that is resistant to most treatments due to its tumour microenvironment. In search of an effective therapeutic agents that can overcome the tumour microenvironment, we analysed the PDAC patients genomic profil...

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Detalles Bibliográficos
Autores principales: Looi, Chin-King, Gan, Li-Lian, Sim, Wynne, Hii, Ling-Wei, Chung, Felicia Fei-Lei, Leong, Chee-Onn, Lim, Wei-Meng, Mai, Chun-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367398/
https://www.ncbi.nlm.nih.gov/pubmed/35954379
http://dx.doi.org/10.3390/cancers14153709