The Role of ATR Inhibitors in Ovarian Cancer: Investigating Predictive Biomarkers of Response

Ataxia telangiectasia and Rad-3 related kinase (ATR) signals DNA lesions and replication stress (RS) to the S and G2/M checkpoints and DNA repair pathways making it a promising target to exploit the dysregulated DNA damage response in cancer. ATR inhibitors (ATRi) are under clinical investigation as...

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Detalles Bibliográficos
Autores principales: Bradbury, Alice, Zenke, Frank T., Curtin, Nicola J., Drew, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367423/
https://www.ncbi.nlm.nih.gov/pubmed/35954206
http://dx.doi.org/10.3390/cells11152361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367423/
https://www.ncbi.nlm.nih.gov/pubmed/35954206
http://dx.doi.org/10.3390/cells11152361

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