Targeting Protein Degradation Pathways in Tumors: Focusing on their Role in Hematological Malignancies

SIMPLE SUMMARY: Proteostasis is a balance between protein formation and degradation. All cells maintain their proteome throughout their lifespan. Malignant cells rely on protein degradation mechanisms to replenish cellular supplies of amino acids. Interference with the protein degradation machinery...

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Detalles Bibliográficos
Autores principales: Wolska-Washer, Anna, Smolewski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367439/
https://www.ncbi.nlm.nih.gov/pubmed/35954440
http://dx.doi.org/10.3390/cancers14153778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367439/
https://www.ncbi.nlm.nih.gov/pubmed/35954440
http://dx.doi.org/10.3390/cancers14153778

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