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Targeting Protein Degradation Pathways in Tumors: Focusing on their Role in Hematological Malignancies
SIMPLE SUMMARY: Proteostasis is a balance between protein formation and degradation. All cells maintain their proteome throughout their lifespan. Malignant cells rely on protein degradation mechanisms to replenish cellular supplies of amino acids. Interference with the protein degradation machinery...
Autores principales: | Wolska-Washer, Anna, Smolewski, Piotr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367439/ https://www.ncbi.nlm.nih.gov/pubmed/35954440 http://dx.doi.org/10.3390/cancers14153778 |
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