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Serial Analysis of Gene Mutations and Gene Expression during First-Line Chemotherapy against Metastatic Colorectal Cancer: Identification of Potentially Actionable Targets within the Multicenter Prospective Biomarker Study REVEAL

SIMPLE SUMMARY: The emergence of resistant cells remains a major obstacle for chemotherapy treatment of metastatic colorectal cancers. Improvement of the therapeutic response requires a thorough understanding of the mechanisms of resistance as well as informative biomarkers. In the REVEAL study, we...

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Detalles Bibliográficos
Autores principales: Kumbrink, Jörg, Bohlmann, Lisa, Mamlouk, Soulafa, Redmer, Torben, Peilstöcker, Daniela, Li, Pan, Lorenzen, Sylvie, Algül, Hana, Kasper, Stefan, Hempel, Dirk, Kaiser, Florian, Michl, Marlies, Bartsch, Harald, Neumann, Jens, Klauschen, Frederick, von Bergwelt-Baildon, Michael, Modest, Dominik Paul, Stahler, Arndt, Stintzing, Sebastian, Jung, Andreas, Kirchner, Thomas, Schäfer, Reinhold, Heinemann, Volker, Holch, Julian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367450/
https://www.ncbi.nlm.nih.gov/pubmed/35892888
http://dx.doi.org/10.3390/cancers14153631