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Human surfactant protein D facilitates SARS-CoV-2 pseudotype binding and entry in DC-SIGN expressing cells, and downregulates spike protein induced inflammation

Lung surfactant protein D (SP-D) and Dendritic cell-specific intercellular adhesion molecules-3 grabbing non-integrin (DC-SIGN) are pathogen recognising C-type lectin receptors. SP-D has a crucial immune function in detecting and clearing pulmonary pathogens; DC-SIGN is involved in facilitating dend...

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Detalles Bibliográficos
Autores principales: Beirag, Nazar, Kumar, Chandan, Madan, Taruna, Shamji, Mohamed H., Bulla, Roberta, Mitchell, Daniel, Murugaiah, Valarmathy, Neto, Martin Mayora, Temperton, Nigel, Idicula-Thomas, Susan, Varghese, Praveen M., Kishore, Uday
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367475/
https://www.ncbi.nlm.nih.gov/pubmed/35967323
http://dx.doi.org/10.3389/fimmu.2022.960733