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DNAM-1-chimeric receptor-engineered NK cells, combined with Nutlin-3a, more effectively fight neuroblastoma cells in vitro: a proof-of-concept study

Adoptive transfer of engineered NK cells, one of clinical approaches to fight cancer, is gaining great interest in the last decade. However, the development of new strategies is needed to improve clinical efficacy and safety of NK cell-based immunotherapy. NK cell-mediated recognition and lysis of t...

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Detalles Bibliográficos
Autores principales: Focaccetti, Chiara, Benvenuto, Monica, Pighi, Chiara, Vitelli, Alessandra, Napolitano, Federico, Cotugno, Nicola, Fruci, Doriana, Palma, Paolo, Rossi, Paolo, Bei, Roberto, Cifaldi, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367496/
https://www.ncbi.nlm.nih.gov/pubmed/35967339
http://dx.doi.org/10.3389/fimmu.2022.886319