A Proof-of-Concept Inhibitor of Endothelial Lipase Suppresses Triple-Negative Breast Cancer Cells by Hijacking the Mitochondrial Function

SIMPLE SUMMARY: Endothelial lipase (EL/LIPG) is a key regulator of tumor cell metabolism. In triple-negative breast cancer (TNBC) cells, we find that the expression of LIPG is associated with long non-coding RNA DANCR and positively correlates with gene signatures of mitochondrial metabolism-oxidati...

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Detalles Bibliográficos
Autores principales: Yang, Rongze, Han, Shuyan, Clayton, Joseph, Haghighatian, Mahan, Tsai, Cheng-Chieh, Yao, Yuan, Li, Pingping, Shen, Jana, Zhou, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367514/
https://www.ncbi.nlm.nih.gov/pubmed/35954428
http://dx.doi.org/10.3390/cancers14153763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367514/
https://www.ncbi.nlm.nih.gov/pubmed/35954428
http://dx.doi.org/10.3390/cancers14153763

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