Chemokine Receptor Expression on T Cells Is Modulated by CAFs and Chemokines Affect the Spatial Distribution of T Cells in Pancreatic Tumors

SIMPLE SUMMARY: The infiltration of T cells in pancreatic tumors has been correlated with better overall survival. However, the dense desmoplastic stroma, mainly composed by cancer-associated fibroblasts (CAFs), can sequester the T cells in the stroma preventing them from reaching the tumor nests. C...

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Detalles Bibliográficos
Autores principales: Gorchs, Laia, Oosthoek, Marlies, Yucel-Lindberg, Tülay, Moro, Carlos Fernández, Kaipe, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367555/
https://www.ncbi.nlm.nih.gov/pubmed/35954489
http://dx.doi.org/10.3390/cancers14153826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367555/
https://www.ncbi.nlm.nih.gov/pubmed/35954489
http://dx.doi.org/10.3390/cancers14153826

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