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Cancer-Associated Fibroblasts in a 3D Engineered Tissue Model Induce Tumor-like Matrix Stiffening and EMT Transition

SIMPLE SUMMARY: The physical properties of a tumor, such as stiffness, are important drivers of tumor progression. However, current in vitro tumor models fail to recapitulate the full range of physical properties observed in solid tumors. Here, we proposed a 3D self-assembly engineered bladder model...

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Detalles Bibliográficos
Autores principales: Millet, Martial, Bollmann, Enola, Ringuette Goulet, Cassandra, Bernard, Geneviève, Chabaud, Stéphane, Huot, Marc-Étienne, Pouliot, Frédéric, Bolduc, Stéphane, Bordeleau, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367573/
https://www.ncbi.nlm.nih.gov/pubmed/35954473
http://dx.doi.org/10.3390/cancers14153810