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Immunorthodontics: PD-L1, a Novel Immunomodulator in Cementoblasts, Is Regulated by HIF-1α under Hypoxia

Recent studies have revealed that hypoxia alters the PD-L1 expression in periodontal cells. HIF-1α is a key regulator for PD-L1. As hypoxia presents a hallmark of an orthodontically induced microenvironment, hypoxic stimulation of PD-L1 expression may play vital roles in immunorthodontics and orthod...

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Detalles Bibliográficos
Autores principales: Yong, Jiawen, Gröger, Sabine, von Bremen, Julia, Meyle, Joerg, Ruf, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367578/
https://www.ncbi.nlm.nih.gov/pubmed/35954195
http://dx.doi.org/10.3390/cells11152350