Circulating Exhausted PD-1(+)CD39(+) Helper CD4 T Cells Are Tumor-Antigen-Specific and Predict Response to PD-1/PD-L1 Axis Blockade

SIMPLE SUMMARY: Not all cancer patients receiving immunotherapy by immune checkpoint blockade experience a clinical benefit. Our study was aimed at identifying biomarkers that could guide the selection of immunotherapy-responsive patients. Immunotherapy targets two major populations of lymphocytes:...

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Detalles Bibliográficos
Autores principales: Martinez-Gomez, Carlos, Michelas, Marie, Scarlata, Clara-Maria, Salvioni, Anna, Gomez-Roca, Carlos, Sarradin, Victor, Lauzéral-Vizcaino, Françoise, Féliu, Virginie, Dupret-Bories, Agnès, Ferron, Gwénaël, Sarini, Jérôme, Devaud, Christel, Delord, Jean-Pierre, Balança, Camille-Charlotte, Martinez, Alejandra, Ayyoub, Maha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367599/
https://www.ncbi.nlm.nih.gov/pubmed/35954341
http://dx.doi.org/10.3390/cancers14153679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367599/
https://www.ncbi.nlm.nih.gov/pubmed/35954341
http://dx.doi.org/10.3390/cancers14153679

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