Preliminary Discovery of Small Molecule Inhibitors of Epidermal Growth Factor Receptor (EGFR) That Bind to the Extracellular Domain

SIMPLE SUMMARY: The Epidermal Growth Factor Receptor (EGFR) is a receptor protein involved in many types of cancers. EGFR can be inhibited by monoclonal antibodies (protein drugs acting on the extracellular domain of the protein) or by ATP-mimic compounds (small molecule drugs blocking the intracell...

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Detalles Bibliográficos
Autores principales: Di Liddo, Rosa, Verona, Marco, Vaccarin, Christian, Acquasaliente, Laura, Schrenk, Sandra, Piccione, Monica, Cenzi, Carola, De Franco, Michele, Dal Prà, Matteo, Ribaudo, Giovanni, Ferlin, Maria Grazia, Conconi, Maria Teresa, Chilin, Adriana, Gandin, Valentina, Marzaro, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367601/
https://www.ncbi.nlm.nih.gov/pubmed/35954311
http://dx.doi.org/10.3390/cancers14153647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367601/
https://www.ncbi.nlm.nih.gov/pubmed/35954311
http://dx.doi.org/10.3390/cancers14153647

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