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Piezo1 activation facilitates ovarian cancer metastasis via Hippo/YAP signaling axis

Ovarian cancer (OC) is a highly malignant cancer with great metastatic potential. Here we aimed to investigate the role of Piezo1, a gene related to the mechanical environment of the tumor, in promoting the metastasis of OC. We performed Piezo1 knockdown in A-1847 cells using small hairpin RNAs, and...

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Detalles Bibliográficos
Autores principales: Xiong, Yanjie, Dong, Liru, Bai, Yun, Tang, Hui, Li, Shuang, Luo, Dan, Liu, Fang, Bai, Jie, Yang, Shikun, Song, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367648/
https://www.ncbi.nlm.nih.gov/pubmed/35942515
http://dx.doi.org/10.1080/19336950.2022.2099381