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MAPKs/AP-1, not NF-κB, is responsible for MCP-1 production in TNF-α-activated adipocytes

Obesity is associated with the infiltration of monocytes/macrophages into adipose tissue in which MCP-1 plays a crucial role. But the regulatory mechanism of MCP-1 expression in adipocytes is not well defined. Our results demonstrated that TNF-α induced abundant MCP-1 production in adipocytes, inclu...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyu, Liu, Zhuangzhuang, Li, Wenjing, Kang, Yuan, Xu, Zhenlu, Li, Ximeng, Gao, Yuan, Qi, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367654/
https://www.ncbi.nlm.nih.gov/pubmed/35941819
http://dx.doi.org/10.1080/21623945.2022.2107786