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MAPKs/AP-1, not NF-κB, is responsible for MCP-1 production in TNF-α-activated adipocytes
Obesity is associated with the infiltration of monocytes/macrophages into adipose tissue in which MCP-1 plays a crucial role. But the regulatory mechanism of MCP-1 expression in adipocytes is not well defined. Our results demonstrated that TNF-α induced abundant MCP-1 production in adipocytes, inclu...
Autores principales: | Zhang, Xiaoyu, Liu, Zhuangzhuang, Li, Wenjing, Kang, Yuan, Xu, Zhenlu, Li, Ximeng, Gao, Yuan, Qi, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367654/ https://www.ncbi.nlm.nih.gov/pubmed/35941819 http://dx.doi.org/10.1080/21623945.2022.2107786 |
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