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Paclitaxel induces cognitive impairment via necroptosis, decreased synaptic plasticity and M1 polarisation of microglia
CONTEXT: Paclitaxel (PTX) leads to chemotherapy brain (chemo-brain) which is characterised by cognitive impairment. It has been reported that necroptosis is associated with cognitive impairment in some neurodegenerative diseases, but it is not clear whether it is related to the development of chemo-...
Autores principales: | Tang, Miao, Zhao, Shuang, Liu, Jia-Xin, Liu, Xin, Guo, Yue-Xian, Wang, Gui-Ying, Wang, Xiu-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367659/ https://www.ncbi.nlm.nih.gov/pubmed/35944285 http://dx.doi.org/10.1080/13880209.2022.2108064 |
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