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A Cross-Tissue Transcriptome-Wide Association Study Identifies Novel Susceptibility Genes for Juvenile Idiopathic Arthritis in Asia and Europe

BACKGROUND: Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children, and its pathogenesis is still unclear. Genome-wide association studies (GWASs) of JIA have identified hundreds of risk factors, but few of them implicated specific biological mechanisms. METHODS: A cros...

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Detalles Bibliográficos
Autores principales: Xu, Jiawen, Ma, Jun, Zeng, Yi, Si, Haibo, Wu, Yuangang, Zhang, Shaoyun, Shen, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367689/
https://www.ncbi.nlm.nih.gov/pubmed/35967305
http://dx.doi.org/10.3389/fimmu.2022.941398