Therapeutic Targeting Notch2 Protects Bone Micro-Vasculatures from Methotrexate Chemotherapy-Induced Adverse Effects in Rats

Intensive cancer chemotherapy is well known to cause bone vasculature disfunction and damage, but the mechanism is poorly understood and there is a lack of treatment. Using a rat model of methotrexate (MTX) chemotherapy (five once-daily dosses at 0.75 mg/kg), this study investigated the roles of the...

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Detalles Bibliográficos
Autores principales: Peymanfar, Yaser, Su, Yu-Wen, Hassanshahi, Mohammadhossein, Xian, Cory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367713/
https://www.ncbi.nlm.nih.gov/pubmed/35954226
http://dx.doi.org/10.3390/cells11152382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367713/
https://www.ncbi.nlm.nih.gov/pubmed/35954226
http://dx.doi.org/10.3390/cells11152382

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