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NADPH and Mitochondrial Quality Control as Targets for a Circadian-Based Fasting and Exercise Therapy for the Treatment of Parkinson’s Disease

Dysfunctional mitochondrial quality control (MQC) is implicated in the pathogenesis of Parkinson’s disease (PD). The improper selection of mitochondria for mitophagy increases reactive oxygen species (ROS) levels and lowers ATP levels. The downstream effects include oxidative damage, failure to main...

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Detalles Bibliográficos
Autores principales: Curtis, William M., Seeds, William A., Mattson, Mark P., Bradshaw, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367803/
https://www.ncbi.nlm.nih.gov/pubmed/35954260
http://dx.doi.org/10.3390/cells11152416