Cargando…
NADPH and Mitochondrial Quality Control as Targets for a Circadian-Based Fasting and Exercise Therapy for the Treatment of Parkinson’s Disease
Dysfunctional mitochondrial quality control (MQC) is implicated in the pathogenesis of Parkinson’s disease (PD). The improper selection of mitochondria for mitophagy increases reactive oxygen species (ROS) levels and lowers ATP levels. The downstream effects include oxidative damage, failure to main...
Autores principales: | Curtis, William M., Seeds, William A., Mattson, Mark P., Bradshaw, Patrick C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367803/ https://www.ncbi.nlm.nih.gov/pubmed/35954260 http://dx.doi.org/10.3390/cells11152416 |
Ejemplares similares
-
Cytoplasmic and Mitochondrial NADPH-Coupled Redox Systems in the Regulation of Aging
por: Bradshaw, Patrick C.
Publicado: (2019) -
COVID-19: Proposing a Ketone-Based Metabolic Therapy as a Treatment to Blunt the Cytokine Storm
por: Bradshaw, Patrick C., et al.
Publicado: (2020) -
The metabolites NADP(+) and NADPH are the targets of the circadian protein Nocturnin (Curled)
por: Estrella, Michael A., et al.
Publicado: (2019) -
Circadian and Metabolic Perspectives in the Role Played by NADPH in Cancer
por: Méndez, Isabel, et al.
Publicado: (2018) -
NADPH oxidase 2 activity in Parkinson’s disease
por: Keeney, Matthew T., et al.
Publicado: (2022)