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Taste Receptor Activation in Tracheal Brush Cells by Denatonium Modulates ENaC Channels via Ca(2+), cAMP and ACh

Mucociliary clearance is a primary defence mechanism of the airways consisting of two components, ciliary beating and transepithelial ion transport (I(SC)). Specialised chemosensory cholinergic epithelial cells, named brush cells (BC), are involved in regulating various physiological and immunologic...

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Detalles Bibliográficos
Autores principales: Hollenhorst, Monika I., Kumar, Praveen, Zimmer, Maxim, Salah, Alaa, Maxeiner, Stephan, Elhawy, Mohamed Ibrahem, Evers, Saskia B., Flockerzi, Veit, Gudermann, Thomas, Chubanov, Vladimir, Boehm, Ulrich, Krasteva-Christ, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367940/
https://www.ncbi.nlm.nih.gov/pubmed/35954259
http://dx.doi.org/10.3390/cells11152411