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Taste Receptor Activation in Tracheal Brush Cells by Denatonium Modulates ENaC Channels via Ca(2+), cAMP and ACh
Mucociliary clearance is a primary defence mechanism of the airways consisting of two components, ciliary beating and transepithelial ion transport (I(SC)). Specialised chemosensory cholinergic epithelial cells, named brush cells (BC), are involved in regulating various physiological and immunologic...
Autores principales: | Hollenhorst, Monika I., Kumar, Praveen, Zimmer, Maxim, Salah, Alaa, Maxeiner, Stephan, Elhawy, Mohamed Ibrahem, Evers, Saskia B., Flockerzi, Veit, Gudermann, Thomas, Chubanov, Vladimir, Boehm, Ulrich, Krasteva-Christ, Gabriela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367940/ https://www.ncbi.nlm.nih.gov/pubmed/35954259 http://dx.doi.org/10.3390/cells11152411 |
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