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Cytosolic HMGB1 Mediates LPS-Induced Autophagy in Microglia by Interacting with NOD2 and Suppresses Its Proinflammatory Function

The high mobility group box 1 (HMGB1), a well-known danger-associated molecule pattern (DAMP) molecule, is a non-histone chromosomal protein localized in the nucleus under normal physiological conditions. HMGB1 exhibits diverse functions depending on its subcellular location. In the present study, w...

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Detalles Bibliográficos
Autores principales: Kim, Seung-Woo, Oh, Sang-A, Seol, Song-I, Davaanyam, Dashdulam, Lee, Ja-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368039/
https://www.ncbi.nlm.nih.gov/pubmed/35954253
http://dx.doi.org/10.3390/cells11152410