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Diploid Wheats: Are They Less Immunogenic for Non-Celiac Wheat Sensitive Consumers?
Non-celiac wheat sensitivity (NCWS) is a clinical entity induced by the ingestion of gluten that leads to intestinal and/or extraintestinal symptoms, and is diagnosed when celiac disease and wheat allergy have been ruled out. In addition to gluten, other grains’ components, including amylase trypsin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368055/ https://www.ncbi.nlm.nih.gov/pubmed/35954233 http://dx.doi.org/10.3390/cells11152389 |
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author | Rotondi Aufiero, Vera Sapone, Anna Mazzarella, Giuseppe |
author_facet | Rotondi Aufiero, Vera Sapone, Anna Mazzarella, Giuseppe |
author_sort | Rotondi Aufiero, Vera |
collection | PubMed |
description | Non-celiac wheat sensitivity (NCWS) is a clinical entity induced by the ingestion of gluten that leads to intestinal and/or extraintestinal symptoms, and is diagnosed when celiac disease and wheat allergy have been ruled out. In addition to gluten, other grains’ components, including amylase trypsin inhibitors (ATIs) and fermentable short-chain carbohydrates (FODMAPs), may trigger symptoms in NCWS subjects. Several studies suggest that, compared with tetraploid and hexaploid modern wheats, ancient diploid wheats species could possess a lower immunogenicity for subjects suffering from NCWS. This review aims to discuss available evidence related to the immunological features of diploid wheats compared to common wheats, and at outlining new dietary opportunities for NCWS subjects. |
format | Online Article Text |
id | pubmed-9368055 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93680552022-08-12 Diploid Wheats: Are They Less Immunogenic for Non-Celiac Wheat Sensitive Consumers? Rotondi Aufiero, Vera Sapone, Anna Mazzarella, Giuseppe Cells Review Non-celiac wheat sensitivity (NCWS) is a clinical entity induced by the ingestion of gluten that leads to intestinal and/or extraintestinal symptoms, and is diagnosed when celiac disease and wheat allergy have been ruled out. In addition to gluten, other grains’ components, including amylase trypsin inhibitors (ATIs) and fermentable short-chain carbohydrates (FODMAPs), may trigger symptoms in NCWS subjects. Several studies suggest that, compared with tetraploid and hexaploid modern wheats, ancient diploid wheats species could possess a lower immunogenicity for subjects suffering from NCWS. This review aims to discuss available evidence related to the immunological features of diploid wheats compared to common wheats, and at outlining new dietary opportunities for NCWS subjects. MDPI 2022-08-03 /pmc/articles/PMC9368055/ /pubmed/35954233 http://dx.doi.org/10.3390/cells11152389 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Rotondi Aufiero, Vera Sapone, Anna Mazzarella, Giuseppe Diploid Wheats: Are They Less Immunogenic for Non-Celiac Wheat Sensitive Consumers? |
title | Diploid Wheats: Are They Less Immunogenic for Non-Celiac Wheat Sensitive Consumers? |
title_full | Diploid Wheats: Are They Less Immunogenic for Non-Celiac Wheat Sensitive Consumers? |
title_fullStr | Diploid Wheats: Are They Less Immunogenic for Non-Celiac Wheat Sensitive Consumers? |
title_full_unstemmed | Diploid Wheats: Are They Less Immunogenic for Non-Celiac Wheat Sensitive Consumers? |
title_short | Diploid Wheats: Are They Less Immunogenic for Non-Celiac Wheat Sensitive Consumers? |
title_sort | diploid wheats: are they less immunogenic for non-celiac wheat sensitive consumers? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368055/ https://www.ncbi.nlm.nih.gov/pubmed/35954233 http://dx.doi.org/10.3390/cells11152389 |
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