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Genetically Engineered Pigs as Efficient Salivary Gland Bioreactors for Production of Therapeutically Valuable Human Nerve Growth Factor

Farm animal salivary glands hold great potential as efficient bioreactors for production of human therapeutic proteins. Nerve growth factor (NGF) is naturally expressed in animal salivary glands and has been approved for human clinical treatment. This study aims to employ transgenic (TG) pig salivar...

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Detalles Bibliográficos
Autores principales: Zeng, Fang, Liao, Sha, Kuang, Zhe, Zhu, Qingchun, Wei, Hengxi, Shi, Junsong, Zheng, Enqin, Xu, Zheng, Huang, Sixiu, Hong, Linjun, Gu, Ting, Yang, Jie, Yang, Huaqiang, Cai, Gengyuan, Moisyadi, Stefan, Urschitz, Johann, Li, Zicong, Wu, Zhenfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368069/
https://www.ncbi.nlm.nih.gov/pubmed/35954224
http://dx.doi.org/10.3390/cells11152378