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Genetically Engineered Pigs as Efficient Salivary Gland Bioreactors for Production of Therapeutically Valuable Human Nerve Growth Factor
Farm animal salivary glands hold great potential as efficient bioreactors for production of human therapeutic proteins. Nerve growth factor (NGF) is naturally expressed in animal salivary glands and has been approved for human clinical treatment. This study aims to employ transgenic (TG) pig salivar...
Autores principales: | Zeng, Fang, Liao, Sha, Kuang, Zhe, Zhu, Qingchun, Wei, Hengxi, Shi, Junsong, Zheng, Enqin, Xu, Zheng, Huang, Sixiu, Hong, Linjun, Gu, Ting, Yang, Jie, Yang, Huaqiang, Cai, Gengyuan, Moisyadi, Stefan, Urschitz, Johann, Li, Zicong, Wu, Zhenfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368069/ https://www.ncbi.nlm.nih.gov/pubmed/35954224 http://dx.doi.org/10.3390/cells11152378 |
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