Electrophysiology of Endolysosomal Two-Pore Channels: A Current Account

Two-pore channels TPC1 and TPC2 are ubiquitously expressed pathophysiologically relevant proteins that reside on endolysosomal vesicles. Here, we review the electrophysiology of these channels. Direct macroscopic recordings of recombinant TPCs expressed in enlarged lysosomes in mammalian cells or va...

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Detalles Bibliográficos
Autores principales: Patel, Sandip, Yuan, Yu, Chen, Cheng-Chang, Jaślan, Dawid, Gunaratne, Gihan, Grimm, Christian, Rahman, Taufiq, Marchant, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368155/
https://www.ncbi.nlm.nih.gov/pubmed/35954212
http://dx.doi.org/10.3390/cells11152368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368155/
https://www.ncbi.nlm.nih.gov/pubmed/35954212
http://dx.doi.org/10.3390/cells11152368

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