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Regulation of APD and Force by the Na(+)/Ca(2+) Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue

The physiological importance of NCX in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is not well characterized but may depend on the relative strength of the current, compared to adult cardiomyocytes, and on the exact spatial arrangement of proteins involved in Ca(2+) extrus...

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Detalles Bibliográficos
Autores principales: Ismaili, Djemail, Gurr, Katrin, Horváth, András, Yuan, Lei, Lemoine, Marc D., Schulz, Carl, Sani, Jascha, Petersen, Johannes, Reichenspurner, Hermann, Kirchhof, Paulus, Jespersen, Thomas, Eschenhagen, Thomas, Hansen, Arne, Koivumäki, Jussi T., Christ, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368200/
https://www.ncbi.nlm.nih.gov/pubmed/35954268
http://dx.doi.org/10.3390/cells11152424