Investigation of Radiotracer Metabolic Stability In Vitro with CYP-Overexpressing Hepatoma Cell Lines

The characterization of novel radiotracers toward their metabolic stability is an essential part of their development. While in vitro methods such as liver microsome assays or ex vivo blood or tissue samples provide information on overall stability, little or no information is obtained on cytochrome...

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Detalles Bibliográficos
Autores principales: Lemm, Sandy, Köhler, Susanne, Wodtke, Robert, Jung, Friedrich, Küpper, Jan-Heiner, Pietzsch, Jens, Laube, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368227/
https://www.ncbi.nlm.nih.gov/pubmed/35954291
http://dx.doi.org/10.3390/cells11152447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368227/
https://www.ncbi.nlm.nih.gov/pubmed/35954291
http://dx.doi.org/10.3390/cells11152447

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