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Hydrocephalus in Nfix(−/−) Mice Is Underpinned by Changes in Ependymal Cell Physiology

Nuclear factor one X (NFIX) is a transcription factor required for normal ependymal development. Constitutive loss of Nfix in mice (Nfix(−/−)) is associated with hydrocephalus and sloughing of the dorsal ependyma within the lateral ventricles. Previous studies have implicated NFIX in the transcripti...

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Detalles Bibliográficos
Autores principales: Harkins, Danyon, Harvey, Tracey J., Atterton, Cooper, Miller, Ingrid, Currey, Laura, Oishi, Sabrina, Kasherman, Maria, Davila, Raul Ayala, Harris, Lucy, Green, Kathryn, Piper, Hannah, Parton, Robert G., Thor, Stefan, Cooper, Helen M., Piper, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368351/
https://www.ncbi.nlm.nih.gov/pubmed/35954220
http://dx.doi.org/10.3390/cells11152377