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Integrated CRISPR-Cas9 System-Mediated Knockout of IFN-γ and IFN-γ Receptor 1 in the Vero Cell Line Promotes Viral Susceptibility

The current pandemic and the possible emergence of new viruses urgently require the rapid development of antiviral vaccines and therapeutics. However, some viruses or newly generated variants are difficult to culture in common cell types or exhibit low viral susceptibility in vivo, making it difficu...

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Detalles Bibliográficos
Autores principales: Kim, Suyeon, Nowakowska, Aleksandra, Kim, Young Bong, Shin, Ha Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368479/
https://www.ncbi.nlm.nih.gov/pubmed/35897807
http://dx.doi.org/10.3390/ijms23158217